Mass General Brigham News
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news.massgeneralbrigham.orgPHARMACEUTICALS AND DRUG DEVELOPMENT
People with Parkinson’s disease who carried the Melanocortin 1 receptor (MC1R) loss-of-function variants experienced 30% to 50% faster motor decline than non-carriers across two independent cohorts. More than 60% of Parkinson’s patients of European descent carry at least one of these variants, suggesting that the finding may apply to a large subgroup of patients.
JACKSON SCHUMACHERMASS GENERAL BRIGHAM NEUROSCIENCE INSTITUTE
INFECTIOUS DISEASES AND IMMUNITY
Mass General Brigham study found distinct immune changes preceding multiple sclerosis relapse, providing new insight into how Epstein-Barr virus reactivation may trigger an MS attack in people with genetic risk factors.