Fitting Evolutionary Models to Sequence Data: Model Selection Using AIC, BIC and MEGA

In evolutionary bioinformatics, after understanding the range of available nucleotide and amino-acid substitution models and their underlying mathematical assumptions (including detailed treatment of the Jukes–Cantor and Kimura two-parameter models), the critical practical question arises: Which substitution model should be used for a given data set? Simply choosing the most complex model with the largest number […] The post Fitting Evolutionary Models to Sequence Data: Model Selection Using AIC, BIC and MEGA appeared first on RathBiotaClan.